Description

Methyl (+/-)-trans-4-Pyridin-4-Yl-Pyrrolidine-3-Carboxylate is a high-purity chiral pyrrolidine derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its versatile scaffold, which is integral to constructing complex molecules with specific three-dimensional configurations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating advanced, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis: Used as a precursor or ligand in catalytic systems to induce chirality in synthetic reactions.
• Medicinal Chemistry Research: A versatile scaffold for constructing focused libraries in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study biological pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value compounds under cGMP conditions where required.

Basic Information

Product Name	Methyl (+/-)-trans-4-Pyridin-4-Yl-Pyrrolidine-3-Carboxylate
CAS No.	1187933-21-6
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	Methyl trans-4-(pyridin-4-yl)pyrrolidine-3-carboxylate; (±)-trans-Methyl 4-(4-pyridyl)pyrrolidine-3-carboxylate; trans-4-Pyridin-4-yl-pyrrolidine-3-carboxylic acid methyl ester; 3-Pyrrolidinecarboxylic acid, 4-(4-pyridinyl)-, methyl ester, trans-(±)-; Methyl 4-(4-pyridyl)-3-pyrrolidinecarboxylate (trans racemate); 1187933-21-6; trans-rac-Methyl 4-(pyridin-4-yl)pyrrolidine-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl (+/-)-trans-4-Pyridin-4-Yl-Pyrrolidine-3-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for advanced research and synthesis. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profile via techniques like HPLC, NMR, and MS, is supplied with each shipment to guarantee reproducible results and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.