Description

1,7-Diaza-Spiro[4.5]Decane-7-Carboxylic Acid tert-Butyl Ester Oxalate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing spirocyclic compounds in drug discovery and lead optimization programs.
• Protease Inhibitor Development: Used in the research and development of inhibitors targeting specific enzymatic pathways.
• Chemical Biology: Employed as a tool compound or building block for probing biological systems and protein-ligand interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	1,7-Diaza-Spiro[4.5]Decane-7-Carboxylic Acid tert-Butyl Ester Oxalate
CAS No.	1187932-79-1
Molecular Formula	C15H24N2O5
Molecular Weight	312.36 g/mol
Synonyms	tert-Butyl 1,7-diaza-spiro[4.5]decane-7-carboxylate oxalate; 1,7-Diaza-spiro[4.5]decane-7-carboxylic acid, 1,1-dimethylethyl ester, ethanedioate (1:1); 7-(tert-Butoxycarbonyl)-1,7-diaza-spiro[4.5]decane oxalate; 1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester oxalate salt; Boc-1,7-Diaza-spiro[4.5]decane oxalate; 1,7-Diazaspiro[4.5]decane-7-carboxylic acid, 1,1-dimethylethyl ester, oxalate
EINECS	Contact for details

Quality Control

Our 1,7-Diaza-Spiro[4.5]Decane-7-Carboxylic Acid tert-Butyl Ester Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.