Description

3-Bromo-5-Methyl-Pyridine Hydrochloride is a high-purity organic salt derivative of a halogenated pyridine, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a reactive bromine substituent and a stabilized hydrochloride form, which is essential for precise molecular construction and scale-up. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new generation herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, liquid crystals, or organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-5-Methyl-Pyridine Hydrochloride
CAS No.	1187932-48-4
Molecular Formula	C6H7BrClN
Molecular Weight	208.48 g/mol
Synonyms	5-Methyl-3-bromopyridine hydrochloride; 3-Bromo-5-picoline hydrochloride; 3-Bromo-5-methylpyridine HCl; 3-Bromo-5-methylpyridine, hydrochloride; 5-Bromo-3-methylpyridine hydrochloride (common numbering); Pyridine, 3-bromo-5-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methyl-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.