Description

Ethyl 5-Aminomethyl-Imidazo[1,5-A]Pyridine-1-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1187932-36-0. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing complex molecules in preclinical and clinical development pipelines.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Development: The aminomethyl group provides a handle for conjugation, useful in creating chemical probes for biological target identification.

Basic Information

Product Name	Ethyl 5-Aminomethyl-Imidazo[1,5-A]Pyridine-1-Carboxylate Hydrochloride
CAS No.	1187932-36-0
Molecular Formula	C12H16N3O2 • HCl
Molecular Weight	269.73 g/mol (Free base: 234.28 g/mol)
Synonyms	1H-Imidazo[1,5-a]pyridine-1-carboxylic acid, 5-(aminomethyl)-, ethyl ester, hydrochloride; Ethyl 5-(aminomethyl)imidazo[1,5-a]pyridine-1-carboxylate hydrochloride; 5-Aminomethyl-imidazo[1,5-a]pyridine-1-carboxylic acid ethyl ester HCl; 1187932-36-0; Imidazopyridine derivative intermediate; Aminomethyl imidazopyridine ester HCl salt.
EINECS	Contact for details

Quality Control

Our Ethyl 5-Aminomethyl-Imidazo[1,5-A]Pyridine-1-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.