Description

2-Phenyl-2,7-Diaza-Spiro[4.4]Nonane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its complex spirocyclic and diaza structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial manufacturing of candidate drugs.
• Bioconjugation & Probe Development: Its amine functionality allows for derivatization to create biochemical probes and diagnostic tools.
• Academic Research: Employed in universities and research institutes for studying spirocyclic compound properties and reaction mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Product Name	2-Phenyl-2,7-Diaza-Spiro[4.4]Nonane Dihydrochloride
CAS No.	1187930-60-4
Molecular Formula	C17H21Cl2N3
Molecular Weight	338.27 g/mol
Synonyms	2-Phenyl-2,7-diazaspiro[4.4]nonane dihydrochloride; 2,7-Diaza-spiro[4.4]nonane, 2-phenyl-, dihydrochloride; 2-Phenyl-2,7-diazaspiro[4.4]nonane hydrochloride; 2-Phenyl-2,7-diazaspiro[4.4]nonane HCl; 2-Phenyl-2,7-diazaspiro[4.4]nonane, 2HCl; 2-Phenyl-2,7-diazaspiro[4.4]nonane dihydrochloride salt; 1187930-60-4; Spiro[4.4]nonane-2,7-diamine, N2-phenyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Phenyl-2,7-Diaza-Spiro[4.4]Nonane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.