Description

n-Boc-2-Amino-5-Hydroxypyridine CAS NO 1187930-13-7 is a protected amino-hydroxypyridine derivative, serving as a versatile and high-purity building block in advanced organic synthesis. Its core value lies in providing a reactive scaffold where both the amino and hydroxyl groups are available for selective functionalization, crucial for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific pyridine-based motifs.

Basic Information

Product Name	n-Boc-2-Amino-5-Hydroxypyridine
CAS No.	1187930-13-7
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	2-Amino-5-hydroxypyridine 1-Boc derivative; tert-Butyl (5-hydroxy-2-pyridinyl)carbamate; 5-Hydroxy-2-pyridinamine, N-BOC-protected; Boc-2-Amino-5-Hydroxypyridine; N-(tert-Butoxycarbonyl)-2-amino-5-hydroxypyridine; 2-((tert-Butoxycarbonyl)amino)-5-hydroxypyridine; 1187930-13-7; (5-Hydroxypyridin-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-2-Amino-5-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for production, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.