Description

4,7-Diaza-Spiro[2.5]Octane-4-Carboxylic Acid Benzyl Ester Oxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those with spirocyclic or constrained ring systems.
• Drug Discovery & Medicinal Chemistry: Used in research for constructing novel chemical libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Protease Inhibitor Development: Serves as a precursor or core scaffold in the development of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at scale.

Basic Information

Product Name	4,7-Diaza-Spiro[2.5]Octane-4-Carboxylic Acid Benzyl Ester Oxalate
CAS No.	1187930-05-7
Molecular Formula	C16H20N2O5
Molecular Weight	320.34 g/mol
Synonyms	4,7-Diaza-spiro[2.5]octane-4-carboxylic acid benzyl ester oxalate; Benzyl 4,7-diaza-spiro[2.5]octane-4-carboxylate oxalate; 4-Carboxy-4,7-diaza-spiro[2.5]octane benzyl ester oxalate; 4,7-Diazaspiro[2.5]octane-4-carboxylic acid, phenylmethyl ester, ethanedioate (1:1); 1187930-05-7; 4,7-Diaza-spiro[2.5]octane-4-carboxylic acid benzyl ester (oxalate salt)
EINECS	Contact for details

Quality Control

Our 4,7-Diaza-Spiro[2.5]Octane-4-Carboxylic Acid Benzyl Ester Oxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.