Description

2-(Piperidin-4-Yloxy)Nicotinic Acid Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern drug discovery. Its core value lies in its unique molecular scaffold, which combines a nicotinic acid moiety with a piperidine ether linkage, making it a versatile precursor for synthesizing bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds to study biological pathways.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and early-stage development of new active substances.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Library Synthesis: Used to create diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-(Piperidin-4-Yloxy)Nicotinic Acid Hydrochloride
CAS No.	1187930-03-5
Molecular Formula	C11H15ClN2O3
Molecular Weight	258.70 g/mol
Synonyms	2-[(Piperidin-4-yl)oxy]nicotinic acid hydrochloride; 2-(4-Piperidyloxy)nicotinic acid hydrochloride; Nicotinic acid, 2-(4-piperidinyloxy)-, hydrochloride; 2-(Piperidin-4-yloxy)pyridine-3-carboxylic acid hydrochloride; 3-Pyridinecarboxylic acid, 2-(4-piperidinyloxy)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-4-Yloxy)Nicotinic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.