Description

(R)-2-Hydroxy-3-(3-Methoxy-Phenyl)-Propionic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis and pharmaceutical development. Its defined stereochemistry and functional groups make it a valuable building block for constructing complex molecules with specific biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective reactions to introduce the (R)-configured hydroxy acid moiety into target molecules.
• Fine Chemical Production: Serves as a building block for the synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: Employed in chemical research for methodological studies in organic synthesis, catalysis, and the development of new chiral ligands or catalysts.
• Agrochemical Intermediate: Potential use in the synthesis of chiral active ingredients for crop protection products.

Basic Information

Item	Details
Product Name	(R)-2-Hydroxy-3-(3-Methoxy-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	1187928-98-8
Molecular Formula	C₁₂H₁₆O₄
Molecular Weight	224.25 g/mol
Synonyms	(R)-Ethyl 2-Hydroxy-3-(3-methoxyphenyl)propanoate; (R)-Ethyl 3-(3-Methoxyphenyl)-2-hydroxypropionate; (R)-2-Hydroxy-3-(3-methoxyphenyl)propionic Acid Ethyl Ester; (R)-3-(3-Methoxyphenyl)-2-hydroxypropionic Acid Ethyl Ester; (R)-O-Desmethyl Venlafaxine Ethyl Ester Intermediate; (R)-ODV Ethyl Ester; (R)-Enantiomer of Ethyl 2-Hydroxy-3-(3-methoxyphenyl)propionate
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-3-(3-Methoxy-Phenyl)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (typically >98.5%), enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.