Description

1-(3-Methoxy-Pyridin-2-Yl)Piperazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound is valued for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical companies engaged in drug discovery, process development, and commercial-scale API production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API (Active Pharmaceutical Ingredient) Synthesis: Used in the production pathway for final active drug substances targeting various disease areas.
• Chemical Research & Development: Serves as a versatile scaffold for creating new chemical entities (NCEs) in academic and industrial R&D labs.
• Preclinical & Clinical Trial Material Production: Supplied for the manufacture of compounds required for toxicology studies and clinical trial batches.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-(3-Methoxy-Pyridin-2-Yl)Piperazine Dihydrochloride
CAS No.	1187928-25-1
Molecular Formula	C10H16Cl2N3O
Molecular Weight	265.16 g/mol
Synonyms	1-(3-Methoxypyridin-2-yl)piperazine dihydrochloride; 2-(Piperazin-1-yl)-3-methoxypyridine dihydrochloride; 3-Methoxy-2-(1-piperazinyl)pyridine dihydrochloride; 1-(3-Methoxy-2-pyridinyl)piperazine dihydrochloride; 1-(3-Methoxypyridin-2-yl)piperazine hydrochloride (1:2); 1187928-25-1; UNII-8V3X6W8Q8H
EINECS	Contact for details

Quality Control

Our 1-(3-Methoxy-Pyridin-2-Yl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and current industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.