Description

2,4-Dichloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine Hcl is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187830-87-0. This heterocyclic compound is a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct the core structure of target APIs.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Agrochemical Research: Potential application as an intermediate in the development of novel herbicides or pesticides, leveraging its heterocyclic chlorinated structure.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2,4-Dichloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine Hcl
CAS No.	1187830-87-0
Molecular Formula	C8H8Cl3N
Molecular Weight	240.51 g/mol
Synonyms	2,4-Dichloro-6,7-dihydro-5H-cyclopenta[b]pyridine hydrochloride; 5H-Cyclopenta[b]pyridine, 2,4-dichloro-6,7-dihydro-, hydrochloride; 2,4-Dichloro-5,6,7,8-tetrahydroquinoline hydrochloride; 2,4-Dichlorocyclopentapyridine HCl; 1187830-87-0; 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[b]pyridine HCl salt
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.