Description

2-Amino-4-Bromo-5-Chloropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Utilized to prepare novel nitrogen-containing ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and diagnostic agents in life science research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	2-Amino-4-Bromo-5-Chloropyridine
CAS No.	1187449-01-9
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	5-Chloro-4-bromopyridin-2-amine; 4-Bromo-5-chloro-2-pyridinamine; 2-Pyridinamine, 4-bromo-5-chloro-; 4-Bromo-5-chloro-2-aminopyridine; 2-Amino-4-bromo-5-chloro-pyridine; 5-Chloro-4-bromo-2-aminopyridine; 4-Bromo-5-chloro-2-amino-pyridine; 2-Amino-5-chloro-4-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Bromo-5-Chloropyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.