Description

Ethyl 5-Bromo-2,3-Difluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the 5-bromo-2,3-difluorophenyl moiety into complex molecular architectures, enabling precise structural modifications. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of difluorinated aromatic systems.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds.
• Material Science: Used in the development of advanced polymers and specialty chemicals with enhanced stability and performance characteristics.

Basic Information

Product Name	Ethyl 5-Bromo-2,3-Difluorobenzoate
CAS No.	1187386-10-2
Molecular Formula	C9H7BrF2O2
Molecular Weight	265.05 g/mol
Synonyms	5-Bromo-2,3-difluorobenzoic Acid Ethyl Ester; Ethyl 5-Bromo-2,3-difluorobenzoate; Benzoic acid, 5-bromo-2,3-difluoro-, ethyl ester; 2,3-Difluoro-5-bromobenzoic Acid Ethyl Ester; 5-Bromo-2,3-difluorobenzoic Acid Ethyl Ester; Ethyl 5-bromo-2,3-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2,3-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.