Description

Benzyl 1-(4-Bromophenyl)Cyclopropylcarbamate CAS NO 1187386-06-6 is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropylcarbamate structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific biological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the development and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring the 1-(4-bromophenyl)cyclopropyl moiety.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme mechanisms and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Benzyl 1-(4-Bromophenyl)Cyclopropylcarbamate
CAS No.	1187386-06-6
Molecular Formula	C17H16BrNO2
Molecular Weight	346.22 g/mol
Synonyms	Carbamic acid, N-[1-(4-bromophenyl)cyclopropyl]-, phenylmethyl ester; Benzyl N-[1-(4-bromophenyl)cyclopropyl]carbamate; 1-(4-Bromophenyl)cyclopropanamine, N-(benzyloxycarbonyl)-; Z-1-(4-Bromophenyl)cyclopropylamine; Cbz-1-(4-Bromophenyl)cyclopropylamine; (1-(4-Bromophenyl)cyclopropyl)carbamic acid benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 1-(4-Bromophenyl)Cyclopropylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.