Description

1-(5-Bromo-6-Methylpyridin-2-Yl)Piperazine, Hcl is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187386-04-4. This compound is a critical building block in modern medicinal chemistry, valued for its piperazine-pyridine hybrid structure which is instrumental in modulating biological activity. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the manufacturing process of potential APIs.
• Biochemical Research: Employed in academic and industrial R&D for probing biological pathways and target interactions.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and process development projects.

Basic Information

Item	Detail
Product Name	1-(5-Bromo-6-Methylpyridin-2-Yl)Piperazine, Hcl
CAS No.	1187386-04-4
Molecular Formula	C11H15BrClN3
Molecular Weight	304.61 g/mol
Synonyms	1-(5-Bromo-6-methyl-2-pyridinyl)piperazine hydrochloride; 5-Bromo-6-methyl-2-(piperazin-1-yl)pyridine hydrochloride; 1-(5-Bromo-6-methylpyridin-2-yl)piperazine hydrochloride; Piperazine, 1-(5-bromo-6-methyl-2-pyridinyl)-, hydrochloride (1:1); 1187386-04-4; 5-Bromo-6-methyl-2-piperazin-1-ylpyridine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-6-Methylpyridin-2-Yl)Piperazine, Hcl adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the material must be kept under dry, inert conditions to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.