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2-(5-Bromopyridin-3-Yl)-5-Propyl-1,3,4-Oxadiazole CAS NO 1187385-81-4


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CAS No.:1187385-81-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(5-Bromopyridin-3-Yl)-5-Propyl-1,3,4-Oxadiazole is a high-purity, heterocyclic organic compound featuring a bromopyridine core fused with a 1,3,4-oxadiazole ring, serving as a critical advanced pharmaceutical intermediate and versatile building block for medicinal chemistry. Its unique molecular architecture makes it indispensable for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery. This compound is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex, target-specific molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
  • Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and combinatorial chemistry for lead optimization.
  • Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with specific modes of action.
  • Material Science: Potential monomer or additive for creating specialty polymers with specific electronic or optical properties.
  • Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
  • Academic & Industrial R&D: Fundamental research tool in organic synthesis and heterocyclic chemistry for developing new methodologies.

Basic Information

Product Name 2-(5-Bromopyridin-3-Yl)-5-Propyl-1,3,4-Oxadiazole
CAS No. 1187385-81-4
Molecular Formula C10H10BrN3O
Molecular Weight 268.11 g/mol
Synonyms 5-Propyl-2-(5-bromopyridin-3-yl)-1,3,4-oxadiazole; 3-(5-Propyl-1,3,4-oxadiazol-2-yl)-5-bromopyridine; 2-(5-Bromo-3-pyridinyl)-5-propyl-1,3,4-oxadiazole; 5-Bromo-3-(5-propyl-1,3,4-oxadiazol-2-yl)pyridine; 1187385-81-4; 5-Propyl-2-(5-bromo-3-pyridyl)-1,3,4-oxadiazole
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Quality Control

Our 2-(5-Bromopyridin-3-Yl)-5-Propyl-1,3,4-Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with exacting research-grade and GMP-for-Intermediate standards where required. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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