Description

1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Cyano-3-[4-[(Methylsulfonyl)Oxy]Butyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound matters because it provides a critical, structurally-defined building block essential for the research and development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this specific intermediate to enable the synthesis of targeted molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex heterocyclic compounds for drug discovery and development.
• Kinase Inhibitor Research: Used in the preparation of candidate molecules targeting various kinase enzymes, a major class in oncology and anti-inflammatory therapeutics.
• Chemical Biology Probes: Serves as a precursor for creating specialized probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific, multi-step synthetic routes.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes from laboratory to pilot plant scale.
• Academic Research: Provides a valuable starting material for universities and research institutes exploring new synthetic methodologies and medicinal chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Cyano-3-[4-[(Methylsulfonyl)Oxy]Butyl]-, 1,1-Dimethylethyl Ester
CAS No.	1187322-57-1
Molecular Formula	C18H23N3O5S
Molecular Weight	393.46 g/mol
Synonyms	tert-Butyl 5-cyano-3-(4-((methylsulfonyl)oxy)butyl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-cyano-3-(4-(methylsulfonyloxy)butyl)-1H-pyrrolo[2,3-b]pyridine; 1-Boc-5-cyano-3-(4-(methylsulfonyloxy)butyl)-7-azaindole; 5-Cyano-3-[4-[(methylsulfonyl)oxy]butyl]-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 5-cyano-3-[4-[(methylsulfonyl)oxy]butyl]-, 1,1-dimethylethyl ester; CAS 1187322-57-1
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Cyano-3-[4-[(Methylsulfonyl)Oxy]Butyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.