Description

(5-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-value, protected intermediate featuring both a hydroxymethyl and a Boc-protected amine group on a pyridine scaffold. This compound is essential for synthetic chemists requiring selective functionalization and controlled reactivity in complex molecule assembly. It is primarily utilized in the research and development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Peptidomimetic Research: The Boc-protected amine makes it valuable for constructing peptide-like structures with enhanced stability.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and enzyme function.
• Material Science: Can be incorporated into the synthesis of functional polymers and organic electronic materials.

Basic Information

Product Name	(5-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1187222-00-9
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	tert-Butyl N-(5-(hydroxymethyl)pyridin-2-yl)carbamate; 2-Pyridinecarboxamide, N-(1,1-dimethylethoxy)-5-(hydroxymethyl)-; Boc-5-hydroxymethyl-2-aminopyridine; 5-(Hydroxymethyl)-2-((tert-butoxycarbonyl)amino)pyridine; 2-((tert-Butoxycarbonyl)amino)-5-(hydroxymethyl)pyridine; 2-Amino-5-hydroxymethylpyridine Boc-protected; N-Boc-5-(hydroxymethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of (5-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.