Description

Ethyl 6-(4-Bromo-3-Formylphenoxy)-2-Ethoxynicotinate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Synthesis: Serves as a crucial building block in multi-step synthetic routes for complex active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by CROs and CDMOs for client-specific contract synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Ethyl 6-(4-Bromo-3-Formylphenoxy)-2-Ethoxynicotinate
CAS No.	1187189-41-8
Molecular Formula	C₁₇H₁₆BrNO₅
Molecular Weight	394.22 g/mol
Synonyms	Ethyl 6-[(4-bromo-3-formyl)phenoxy]-2-ethoxynicotinate; 2-Ethoxy-6-[(4-bromo-3-formyl)phenoxy]nicotinic Acid Ethyl Ester; 6-(4-Bromo-3-formylphenoxy)-2-ethoxy-3-pyridinecarboxylic Acid Ethyl Ester; 1187189-41-8; Ethyl 2-ethoxy-6-(4-bromo-3-formylphenoxy)nicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 6-(4-Bromo-3-Formylphenoxy)-2-Ethoxynicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards where required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.