Description

2-(3-Bromobenzoyl)-5-Methylpyridine CAS NO 1187170-72-4 is a high-purity brominated aromatic ketone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which provides a versatile platform for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators, leveraging the bromine atom for further functionalization.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Intermediate in the production of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies in organic chemistry, including novel ring-forming reactions and heterocycle synthesis.

Basic Information

Product Name	2-(3-Bromobenzoyl)-5-Methylpyridine
CAS No.	1187170-72-4
Molecular Formula	C13H10BrNO
Molecular Weight	276.13 g/mol
Synonyms	5-Methyl-2-(3-bromobenzoyl)pyridine; (3-Bromophenyl)(5-methylpyridin-2-yl)methanone; 2-(3-Bromobenzoyl)-5-picoline; 3-Bromo-α-(5-methyl-2-pyridinyl)benzyl alcohol ketone form; 1187170-72-4; 2-(3-Bromobenzoyl)-5-methylpyridine; Methanone, (3-bromophenyl)(5-methyl-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-(3-Bromobenzoyl)-5-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and compatible with strong acid/organic solvent environments. Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.