Description

3-(2,4-Difluorobenzoyl)-4-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorobenzoyl-substituted pyridine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate its unique fluorinated aromatic moiety into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and anti-infective research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluorobenzoyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands and functional organic molecules for advanced materials.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-(2,4-Difluorobenzoyl)-4-Methylpyridine
CAS No.	1187168-90-6
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	4-Methyl-3-(2,4-difluorobenzoyl)pyridine; 3-(2,4-Difluorobenzoyl)-4-picoline; (2,4-Difluorophenyl)(4-methylpyridin-3-yl)methanone; 4-Methyl-3-(2,4-difluorobenzoyl)pyridine; 1187168-90-6; 3-(2,4-Difluorobenzoyl)-4-methylpyridine
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluorobenzoyl)-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.