Description

2-Chloro-5-(3-Fluorobenzoyl)Pyridine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187168-05-3. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of kinase inhibitors and other small-molecule drugs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyridine structure.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the synthesis of specialized ligands and functionalized polymers.

Basic Information

Product Name	2-Chloro-5-(3-Fluorobenzoyl)Pyridine
CAS No.	1187168-05-3
Molecular Formula	C12H7ClFNO
Molecular Weight	235.64 g/mol
Synonyms	5-(3-Fluorobenzoyl)-2-chloropyridine; 2-Chloro-5-(3-fluorobenzoyl)pyridine; (3-Fluorophenyl)(6-chloropyridin-3-yl)methanone; 3-Fluoro-3'-chloro-5-pyridyl benzophenone; 2-Chloro-5-(m-fluorobenzoyl)pyridine; 1187168-05-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(3-Fluorobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.