Description

2-Methyl-5-(3-Trifluoromethylbenzoyl)Pyridine is a high-value, fluorinated aromatic ketone building block crucial for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific trifluoromethylbenzoylpyridine scaffold into novel molecules.

Application

• As a key synthetic intermediate in the research and production of novel pharmaceutical candidates.
• In the development of agrochemicals, including herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• For the synthesis of ligands and catalysts used in asymmetric catalysis and metal-organic frameworks (MOFs).
• As a building block for advanced materials, such as organic semiconductors and liquid crystals.
• In academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry.
• For the custom synthesis of fluorinated fine chemicals and specialty reagents.

Basic Information

Product Name	2-Methyl-5-(3-Trifluoromethylbenzoyl)Pyridine
CAS No.	1187166-93-3
Molecular Formula	C14H10F3NO
Molecular Weight	265.23 g/mol
Synonyms	5-(3-(Trifluoromethyl)benzoyl)-2-picoline; 2-Picoline, 5-[3-(trifluoromethyl)benzoyl]-; 3'-Trifluoromethyl-2-methyl-5-benzoylpyridine; [3-(Trifluoromethyl)phenyl](6-methyl-3-pyridinyl)methanone; 2-Methyl-5-(3-(trifluoromethyl)benzoyl)pyridine; 5-(α,α,α-Trifluoro-m-toluoyl)-2-picoline
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(3-Trifluoromethylbenzoyl)Pyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.