Description

2-(2-Iodobenzoyl)-6-Methoxypyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct iodobenzoyl and methoxypyridine structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to develop new molecular entities.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) and other metal-catalyzed transformations due to the reactive iodine moiety.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(2-Iodobenzoyl)-6-Methoxypyridine
CAS No.	1187165-03-2
Molecular Formula	C13H10INO2
Molecular Weight	339.13 g/mol
Synonyms	6-Methoxy-2-(2-iodobenzoyl)pyridine; 2-(2-Iodobenzoyl)-6-methoxypyridine; 2-Iodobenzoyl-6-methoxypyridine; (2-Iodophenyl)(6-methoxypyridin-2-yl)methanone; 2-Methoxypyridine-6-(2-iodobenzoyl); 1187165-03-2
EINECS	Contact for details

Quality Control

Our 2-(2-Iodobenzoyl)-6-Methoxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.