Description

2-(3,5-Difluorobenzoyl)-6-Methylpyridine is a high-value, fluorinated pyridine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce difluorobenzoyl motifs into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides and fungicides with enhanced activity and environmental profile.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals, where fluorine substitution tunes electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.
• Academic & Industrial R&D: Utilized in discovery chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.

Basic Information

Product Name	2-(3,5-Difluorobenzoyl)-6-Methylpyridine
CAS No.	1187164-65-3
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	6-Methyl-2-(3,5-difluorobenzoyl)pyridine; (3,5-Difluorophenyl)(6-methylpyridin-2-yl)methanone; 2-(3,5-Difluorobenzoyl)-6-picoline; 2-Pyridinecarboxaldehyde, 6-methyl-, (3,5-difluorophenyl)hydrazone (related); Difluorobenzoyl methylpyridine derivative
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluorobenzoyl)-6-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.