Description

1-(2-Bromobutanoyl)-3,5-Dimethylpiperidine is a specialized brominated piperidine derivative, serving as a crucial synthetic intermediate in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a reactive handle for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel piperidine-based drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the bromobutanoyl moiety can be leveraged for further functionalization.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex molecules in pilot plants and commercial manufacturing.
• Ligand & Catalyst Precursor: Potential use in the preparation of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(2-Bromobutanoyl)-3,5-Dimethylpiperidine
CAS No.	1186653-36-0
Molecular Formula	C11H20BrNO
Molecular Weight	262.19 g/mol
Synonyms	2-Bromo-1-(3,5-dimethylpiperidin-1-yl)butan-1-one; 1-(2-Bromobutyryl)-3,5-dimethylpiperidine; 3,5-Dimethyl-1-(2-bromobutyryl)piperidine; 2-Bromobutyric acid 3,5-dimethylpiperidide; N-(2-Bromobutyryl)-3,5-dimethylpiperidine
EINECS	Contact for details

Quality Control

Our 1-(2-Bromobutanoyl)-3,5-Dimethylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.