Description

3-(Oxolan-3-Yl)-1H-Pyrazol-5-Amine CAS NO 1186609-16-4 is a high-purity heterocyclic organic compound featuring a pyrazole core fused with an oxolane (tetrahydrofuran) ring. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry to create diverse compound libraries for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a core structure for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Institutional Research: A critical reagent for universities and research institutes conducting fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	3-(Oxolan-3-Yl)-1H-Pyrazol-5-Amine
CAS No.	1186609-16-4
Molecular Formula	C7H11N3O
Molecular Weight	153.18 g/mol
Synonyms	3-(Tetrahydrofuran-3-yl)-1H-pyrazol-5-amine; 5-Amino-3-(tetrahydro-3-furanyl)-1H-pyrazole; 3-(Oxolan-3-yl)-1H-pyrazol-5-amine; 3-(3-Furanyl)-1H-pyrazol-5-amine (partially hydrogenated form); THF-pyrazole amine; 3-(3-Tetrahydrofuryl)-5-aminopyrazole; 1186609-16-4; 5-Amino-3-(oxolan-3-yl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 3-(Oxolan-3-Yl)-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.