Description

Methyl 5-(2-(Trifluoromethyl)-2,3-Dihydro-1H-Benzo[D]Imidazol-2-Yl)Pentanoate is a high-value, fluorinated benzimidazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its unique trifluoromethylated heterocyclic structure, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science: Potential precursor for specialty polymers, liquid crystals, or organic electronic materials requiring fluorinated components.
• Chemical Biology: Serves as a probe or linker in the design of enzyme inhibitors and other biologically active molecules for research purposes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in fluorination chemistry and heterocycle synthesis.

Basic Information

Product Name	Methyl 5-(2-(Trifluoromethyl)-2,3-Dihydro-1H-Benzo[D]Imidazol-2-Yl)Pentanoate
CAS No.	1186590-49-7
Molecular Formula	C15H17F3N2O2
Molecular Weight	314.30 g/mol
Synonyms	Methyl 5-[2-(trifluoromethyl)-2,3-dihydro-1H-benzimidazol-2-yl]pentanoate; 2-(Trifluoromethyl)-2,3-dihydro-1H-benzimidazole-2-pentanoic acid methyl ester; 1186590-49-7; Methyl 5-(2-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-yl)pentanoate; Benzimidazole, 2,3-dihydro-2-(trifluoromethyl)-, 2-pentanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(2-(Trifluoromethyl)-2,3-Dihydro-1H-Benzo[D]Imidazol-2-Yl)Pentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material that meets stringent internal standards, and custom purity grades (e.g., >97%, >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.