Description

1H-Pyrrolo[2,3-B]Pyridin-5-Amine, 2-Methyl-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially those targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs, particularly for kinase inhibitors.
• Biochemical Research: Employed in the study of enzyme-substrate interactions and the development of assay probes.
• Organic Synthesis: Utilized in complex organic transformations to introduce the fused pyrrolopyridine amine moiety into target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-5-Amine, 2-Methyl-1-(Phenylsulfonyl)-
CAS No.	1186502-59-9
Molecular Formula	C14H13N3O2S
Molecular Weight	287.34 g/mol
Synonyms	2-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-amine; 1H-Pyrrolo[2,3-b]pyridin-5-amine, 2-methyl-1-(phenylsulfonyl)-; 2-Methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-amine; 5-Amino-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-5-amine; 2-Methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-amine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-5-Amine, 2-Methyl-1-(Phenylsulfonyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.