Description

2,6-Dichloro-3-Iodo-4-(Trifluoromethyl)Pyridine is a highly functionalized pyridine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated and trifluoromethylated structure makes it an exceptionally valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and halogen groups can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for creating functionalized ligands, organic semiconductors, and specialty polymers with specific electronic or photophysical properties.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to create complex biaryl systems.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and mechanisms of action.

Basic Information

Product Name	2,6-Dichloro-3-Iodo-4-(Trifluoromethyl)Pyridine
CAS No.	1186405-02-6
Molecular Formula	C7HCl2F3IN
Molecular Weight	361.89 g/mol
Synonyms	3-Iodo-2,6-dichloro-4-(trifluoromethyl)pyridine; 2,6-Dichloro-3-iodo-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-2,6-dichloro-3-iodopyridine; Pyridine, 2,6-dichloro-3-iodo-4-(trifluoromethyl)-; 1186405-02-6
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-3-Iodo-4-(Trifluoromethyl)Pyridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet the stringent requirements of cGMP and other regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.