Description

3-((3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)Methyl)-5-Iodopyridine is a sophisticated, multi-functional organic building block featuring both a protected hydroxyl group and a halogenated pyridine ring. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides that require specific halogenated heterocyclic structures.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Process Chemistry: Utilized in route scouting and scale-up processes for the commercial manufacturing of fine chemicals.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-((3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)Methyl)-5-Iodopyridine
CAS No.	1186311-02-3
Molecular Formula	C17H29IN2OSi
Molecular Weight	432.42 g/mol
Synonyms	5-Iodo-3-[[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-1-pyrrolidinyl]methyl]pyridine; 3-((3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)Methyl)-5-Iodopyridine; TBDMS-protected pyrrolidine iodopyridine derivative; 1-[(5-Iodopyridin-3-yl)methyl]-3-[(tert-butyldimethylsilyloxy)methyl]pyrrolidine; 5-Iodo-3-((3-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-((3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)Methyl)-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.