Description

6-Iodo-1-(4-Methoxybenzyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One is a high-purity, advanced pharmaceutical intermediate with the CAS number 1186310-96-2. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique molecular scaffold that enables the synthesis of complex, bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, leveraging the iodine moiety for further functionalization via cross-coupling reactions.
• Chemical Biology Probes: Potential use in the development of molecular probes for target identification and validation in biological systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Iodo-1-(4-Methoxybenzyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One
CAS No.	1186310-96-2
Molecular Formula	C₁₅H₁₃IN₂O₃
Molecular Weight	396.18 g/mol
Synonyms	6-Iodo-1-(4-methoxybenzyl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one; 1-(4-Methoxybenzyl)-6-iodo-3H-pyrido[2,3-b][1,4]oxazin-2-one; 1186310-96-2; 6-Iodo-1-[(4-methoxyphenyl)methyl]-3H-pyrido[2,3-b][1,4]oxazin-2-one; Pyrido[2,3-b][1,4]oxazin-2(3H)-one, 6-iodo-1-[(4-methoxyphenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 6-Iodo-1-(4-Methoxybenzyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.