Description

5-Bromo-2-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-3-Methoxypyridine is a high-value, multi-functional organic intermediate featuring a protected hydroxyl group and a brominated pyridine core. This compound matters for its role as a critical building block in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon in the development of small-molecule drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or activity-based probes for target identification and validation.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in synthetic organic chemistry projects focused on new methodologies or complex natural product synthesis.
• Custom Synthesis & Contract Manufacturing: A requested component for bespoke chemical synthesis services provided to the life sciences industry.

Basic Information

Product Name	5-Bromo-2-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-3-Methoxypyridine
CAS No.	1186310-84-8
Molecular Formula	C18H31BrN2O2Si
Molecular Weight	415.45 g/mol
Synonyms	5-Bromo-2-[[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-1-pyrrolidinyl]methyl]-3-methoxypyridine; 3-Methoxy-5-bromo-2-((3-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)pyridine; TBDMS-protected pyrrolidinylmethyl bromomethoxypyridine; 1186310-84-8; 5-Bromo-2-((3-((TBDMS-oxy)methyl)pyrrolidin-1-yl)methyl)-3-methoxypyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-3-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.