Description

2-Chloro-4-Hydroxynicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and hydroxymethylene substituents, makes it a valuable building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive aldehyde and halogen functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and constructing molecular libraries for screening.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials due to its conjugated pyridine core.

Basic Information

Product Name	2-Chloro-4-Hydroxynicotinaldehyde
CAS No.	1186310-65-5
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	2-Chloro-4-hydroxypyridine-5-carbaldehyde; 4-Hydroxy-2-chloronicotinaldehyde; 5-Formyl-2-chloro-4-hydroxypyridine; 2-Chloro-4-hydroxy-5-pyridinecarboxaldehyde; 2-Chloro-4-hydroxynicotinic aldehyde; 2-Chloro-4-oxo-1,4-dihydropyridine-5-carbaldehyde; 1186310-65-5; Aldehyde, 2-chloro-4-hydroxynicotinal
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Hydroxynicotinaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality ensures reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.