Description

2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid methyl ester is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of fluorine atoms and a sulfonamide functional group, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, where the difluoro and sulfonamide motifs can enhance efficacy and environmental profile.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
• Material Science: Potential use in the synthesis of specialty polymers or advanced materials that require fluorinated aromatic components for specific thermal or chemical resistance properties.

Basic Information

Product Name	2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid methyl ester
CAS No.	1186223-50-6
Molecular Formula	C12H13F2NO4S
Molecular Weight	305.30 g/mol
Synonyms	Methyl 2,6-difluoro-3-[(propylsulfonyl)amino]benzoate; 2,6-Difluoro-3-(propylsulfonamido)benzoic acid methyl ester; Benzoic acid, 2,6-difluoro-3-[(propylsulfonyl)amino]-, methyl ester; 3-[(Propylsulfonyl)amino]-2,6-difluorobenzoic acid methyl ester; CAS 1186223-50-6
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.