Description

Dimethyl (3-Trifluoromethylbenzyl)Malonate is a high-value fluorinated malonate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethylbenzyl moiety, which imparts unique electronic and steric properties to target molecules, enhancing their biological activity and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates containing trifluoromethylphenyl groups, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the trifluoromethyl group improves lipophilicity and systemic activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and stability.
• Advanced Polymer Chemistry: Employed in the synthesis of specialty monomers for high-performance, fluorinated polymers with enhanced chemical and thermal resistance.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures via malonate chemistry, including alkylation and condensation reactions.

Basic Information

Product Name	Dimethyl (3-Trifluoromethylbenzyl)Malonate
CAS No.	1186194-84-2
Molecular Formula	C₁₃H₁₃F₃O₄
Molecular Weight	290.24 g/mol
Synonyms	Dimethyl 2-[(3-(trifluoromethyl)phenyl)methyl]propanedioate; Propanedioic acid, 2-[(3-(trifluoromethyl)phenyl)methyl]-, 1,3-dimethyl ester; (3-Trifluoromethylbenzyl)malonic Acid Dimethyl Ester; Dimethyl (3-(Trifluoromethyl)benzyl)malonate; α-((3-Trifluoromethyl)benzyl)malonic Acid Dimethyl Ester; Dimethyl (m-Trifluoromethylbenzyl)malonate; m-Trifluoromethylbenzylmalonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl (3-Trifluoromethylbenzyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.