Description

3-(1,1-Difluoropropyl)-Pyridine is a specialized fluorinated pyridine derivative, a high-value intermediate in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoropropyl group, making it a critical building block for creating novel compounds with tailored properties. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science sectors, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and asymmetric synthesis.
• Material Science Research: Building block for creating fluorinated polymers, liquid crystals, or electronic materials with specific dielectric or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications due to its modifiable pyridine core.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-(1,1-Difluoropropyl)-Pyridine
CAS No.	1186194-56-8
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	3-(1,1-Difluoropropyl)pyridine; Pyridine, 3-(1,1-difluoropropyl)-; 1,1-Difluoropropyl-3-pyridine; 3-Pyridyl-1,1-difluoropropane; 3-(1,1-Difluoropropyl)pyridine (CAS 1186194-56-8); 3-(α,α-Difluoropropyl)pyridine; 3-(1,1-Difluoroprop-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-(1,1-Difluoropropyl)-Pyridine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.