Description

2-Bromo-1-(6-Methoxypyridin-2-Yl)Ethan-1-One is a high-purity brominated pyridinyl ketone building block of significant interest in advanced organic synthesis. This compound serves as a critical electrophilic intermediate for the construction of complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty fine chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-Bromo-1-(6-Methoxypyridin-2-Yl)Ethan-1-One
CAS No.	1186113-50-7
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-1-(6-methoxypyridin-2-yl)ethanone; 2-Bromo-1-(6-methoxy-2-pyridinyl)ethanone; 2-Acetyl-6-methoxypyridine Bromide; α-Bromo-6-methoxy-2-acetylpyridine; 6-Methoxy-2-pyridyl Bromomethyl Ketone; 1-(6-Methoxypyridin-2-yl)-2-bromoethanone; 2-Bromo-1-(6-methoxypyridin-2-yl)ethan-1-one (IUPAC); Bromo(6-methoxy-2-pyridinyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(6-Methoxypyridin-2-Yl)Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications from research to development and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.