Description

6-(3-Propylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid CAS NO 1186112-85-5 is a high-value, multi-functional boronic acid derivative designed for advanced synthetic chemistry. Its core value lies in its role as a key Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Serves as a precursor for creating functionalized organic electronic materials and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: The primary application is as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl/heteroaryl halides.
• Medicinal Chemistry: Enables rapid structure-activity relationship (SAR) studies and library synthesis due to its reactive boronic acid group.
• Chemical Biology: Can be utilized for bioconjugation or as a probe in biochemical assays targeting specific protein interactions.

Basic Information

Product Name	6-(3-Propylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid
CAS No.	1186112-85-5
Molecular Formula	C13H14BF3N4O2S
Molecular Weight	358.15 g/mol
Synonyms	4-(4-(Trifluoromethyl)-1,3-thiazol-2-yl)-6-(propylcarbamoylamino)pyridin-3-ylboronic acid; 6-(3-Propylureido)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-3-ylboronic acid; 3-Pyridineboronic acid, 6-[[(propylamino)carbonyl]amino]-4-[4-(trifluoromethyl)-2-thiazolyl]-; Boronic acid, B-[6-[[(propylamino)carbonyl]amino]-4-[4-(trifluoromethyl)-2-thiazolyl]-3-pyridinyl]-; 1186112-85-5
EINECS	Contact for details

Quality Control

Every batch of 6-(3-Propylureido)-4-(4-(Trifluoromethyl)Thiazol-2-Yl)Pyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.