Description

2-Chloro-6-Isopropoxypyridin-4-Amine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and alkoxylated amine structure, which enables precise molecular modifications for creating complex, high-value compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and custom synthesis houses to build bespoke molecules for client projects.

Basic Information

Product Name	2-Chloro-6-Isopropoxypyridin-4-Amine
CAS No.	1186111-99-8
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	4-Amino-2-chloro-6-isopropoxypyridine; 2-Chloro-6-(1-methylethoxy)-4-pyridinamine; 2-Chloro-6-isopropoxy-4-aminopyridine; 2-Chloro-6-(propan-2-yloxy)pyridin-4-amine; 4-Pyridinamine, 2-chloro-6-(1-methylethoxy)-; 1186111-99-8; 2-Chloro-6-isopropoxy-4-pyridinylamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Isopropoxypyridin-4-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.