Description

4-Trimethylsilylbenzeneboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound matters as a key building block in cross-coupling reactions, enabling the precise construction of complex molecules for research and development. It is primarily needed by pharmaceutical researchers, agrochemical developers, and material scientists working on organosilicon and boron-containing compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A crucial protected reagent for constructing biaryl and heterobiaryl scaffolds in pharmaceutical intermediates.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing novel charge-transport or emissive materials containing silicon and boron.
• Agrochemical Synthesis: Used in the development of new active ingredients by introducing the trimethylsilylphenyl moiety.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organometallic complexes.
• Chemical Biology Probes: Acts as a versatile handle for labeling or modifying biomolecules in probe development.
• Process Chemistry & Scale-up: The pinacol ester protection offers improved stability for handling in multi-step industrial syntheses.

Basic Information

Product Name	4-Trimethylsilylbenzeneboronic Acid Pinacol Ester
CAS No.	1186026-67-4
Molecular Formula	C15H25BO2Si
Molecular Weight	276.26 g/mol
Synonyms	4-(Trimethylsilyl)benzeneboronic acid pinacol ester; (4-Trimethylsilylphenyl)boronic acid pinacol ester; 2-[4-(Trimethylsilyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Trimethylsilyl)phenylboronic acid pinacol ester; Pinacol 4-(Trimethylsilyl)benzeneboronate; B-[4-(Trimethylsilyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-TMS-benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Trimethylsilylbenzeneboronic Acid Pinacol Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.