Description

(4-Chloropyridin-2-Yl)Methanol Hydrochloride CAS NO 1185714-76-4 is a high-purity, functionalized pyridine derivative supplied as a hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive chloropyridine scaffold with a hydroxymethyl handle, enabling precise molecular construction for complex target molecules. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides that require specific chloropyridine motifs for bioactivity.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands for metal catalysis and organocatalysts, leveraging the coordinating ability of the pyridine nitrogen.
• Material Science Research: Intermediate for constructing functional organic molecules used in organic electronics, such as OLEDs or conductive polymers.
• Chemical Biology Probes: Serves as a precursor for labeling reagents and molecular probes used in biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific molecular architecture.

Basic Information

Product Name	(4-Chloropyridin-2-Yl)Methanol Hydrochloride
CAS No.	1185714-76-4
Molecular Formula	C6H7Cl2NO
Molecular Weight	180.03 g/mol
Synonyms	2-(Hydroxymethyl)-4-chloropyridine Hydrochloride; (4-Chloro-2-pyridinyl)methanol Hydrochloride; 4-Chloro-2-pyridinemethanol Hydrochloride; 4-Chloro-2-(hydroxymethyl)pyridine Hydrochloride; 4-Chloro-2-pyridylmethanol HCl; 2-Pyridinemethanol, 4-chloro-, hydrochloride; 4-Chloro-2-pyridylcarbinol hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (4-Chloropyridin-2-Yl)Methanol Hydrochloride is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.