Description

3-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic piperidine-pyridine structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Serves as a key chiral building block for the production of potential Active Pharmaceutical Ingredients (APIs) with high stereochemical purity.
• Chemical Biology Probes: Utilized in the development of specialized probes and tool compounds for studying biological pathways and target validation.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester
CAS No.	1185538-22-0
Molecular Formula	C12H17N3O2
Molecular Weight	235.28 g/mol
Synonyms	Methyl 3-amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylate; 3'-Amino-3',4',5',6'-tetrahydro-2'H-[1,2]bipyridinyl-3-carboxylic acid methyl ester; 3-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester; 1185538-22-0; Methyl 3-amino-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-3'-carboxylate; 3-Amino-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-3'-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development under cGMP guidelines where required and ensure traceability for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.