Description

4-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular research. It is primarily sought by pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) engaged in modern drug discovery programs. The compound, identified by CAS NO 1185536-69-9, offers a strategic advantage in the development of proprietary therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• Neurological & CNS Drug Research: Used in the development of potential therapeutics for neurological disorders, leveraging its specific heterocyclic scaffold.
• Cardiovascular Agent Synthesis: Serves as a building block for novel compounds being investigated for cardiovascular applications.
• Medicinal Chemistry & Lead Optimization: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	4-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester
CAS No.	1185536-69-9
Molecular Formula	C12H19N3O2
Molecular Weight	237.30 g/mol
Synonyms	Methyl 4-amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylate; 4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 4-amino-1,2,3,6-tetrahydro-2,2'-bipyridin-3-yl methyl ester; 1185536-69-9; 4-Amino-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-3-carboxylic acid methyl ester; Methyl 4-amino-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-3,4,5,6-Tetrahydro-2H-[1,2]Bipyridinyl-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.