Description

9-Oxa-2-Azaspiro[5.5]Undecan-1-One is a high-value, spirocyclic heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique bridged structure containing both oxygen and nitrogen atoms makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its spirocyclic scaffold for enhanced biological activity and stability.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The heteroatom framework can be functionalized to create novel ligands for asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and the synthesis of complex natural product analogs in academic and CRO settings.

Basic Information

Product Name	9-Oxa-2-Azaspiro[5.5]Undecan-1-One
CAS No.	1185320-34-6
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	9-Oxa-2-azaspiro[5.5]undecan-1-one; 1-Oxa-4-azaspiro[4.5]decan-3-one (alternative numbering); 2-Aza-9-oxaspiro[5.5]undecan-1-one; Spirocyclic lactam ether; Oxa-azaspiro undecanone; 1-Oxo-9-oxa-2-azaspiro[5.5]undecane; 2-Azaspiro[5.5]undecane-1,9-dione, 9-oxime (related derivative); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 9-Oxa-2-Azaspiro[5.5]Undecan-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.