Description

2-(4-Chloropiperidin-1-Yl)Isonicotinonitrile is a high-purity, functionalized heterocyclic compound with a molecular formula of C11H12ClN3 and a molecular weight of 221.69. This chemical serves as a versatile and valuable pharmacophore and synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its chloropiperidine and cyanopyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Investigated as a monomer or additive for creating polymers with specific electronic or thermal properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Custom Synthesis: Employed by contract research organizations (CROs) and CDMOs for client-specific molecule assembly and scale-up projects.

Basic Information

Item	Details
Product Name	2-(4-Chloropiperidin-1-Yl)Isonicotinonitrile
CAS No.	1185318-26-6
Molecular Formula	C11H12ClN3
Molecular Weight	221.69 g/mol
Synonyms	2-(4-Chloro-1-piperidinyl)isonicotinonitrile; 4-Chloro-1-(4-cyanopyridin-2-yl)piperidine; 2-(4-Chloropiperidin-1-yl)-4-cyanopyridine; 2-(4-Chloro-1-piperidyl)pyridine-4-carbonitrile; 4-Cyano-2-(4-chloropiperidin-1-yl)pyridine; 2-(4-Chloropiperidino)isonicotinonitrile; Isonicotinonitrile, 2-(4-chloro-1-piperidinyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Chloropiperidin-1-Yl)Isonicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the purity meets or exceeds the stated 98+% specification. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.