Description

2-Chloro-5-(Piperidin-3-Ylmethoxymethyl)-Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a well-defined chemical structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on drug discovery programs targeting neurological and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a precursor in the multi-step synthesis of potential new chemical entities (NCEs).
• Biochemical Tool Compound: May be utilized in vitro to study specific biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of clinical trial materials.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Piperidin-3-Ylmethoxymethyl)-Pyridine Dihydrochloride
CAS No.	1185316-47-5
Molecular Formula	C12H18Cl2N2O
Molecular Weight	277.19 g/mol
Synonyms	2-Chloro-5-[(3-piperidinylmethoxy)methyl]pyridine dihydrochloride; 2-Chloro-5-((piperidin-3-ylmethoxy)methyl)pyridine dihydrochloride; 2-Chloro-5-(piperidin-3-ylmethoxymethyl)pyridine hydrochloride (1:2); UNII-6V7Q2J8R4H; 6V7Q2J8R4H; 2-Chloro-5-[(3-piperidinylmethoxy)methyl]pyridine, dihydrochloride; 2-Chloro-5-(3-piperidylmethoxymethyl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Piperidin-3-Ylmethoxymethyl)-Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.