Description

4-Amino-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3'-Carbonitrile Hydrochloride, 98+% C11H15Cln4, Mw: 238.72 is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and manufacturing who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially for neurological and oncological targets.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up API synthesis under GMP conditions.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and receptor binding studies.
• Academic Research: Employed in universities and research institutes for synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	4-Amino-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3'-Carbonitrile Hydrochloride, 98+%
CAS No.	1185316-16-8
Molecular Formula	C11H15ClN4
Molecular Weight	238.72 g/mol
Synonyms	4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carbonitrile hydrochloride; 4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carbonitrile HCl; 3'-Cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-amine hydrochloride; 4-Amino-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-3'-carbonitrile hydrochloride; 1185316-16-8; 4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carbonitrile monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3'-Carbonitrile Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture uptake and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.