Description

(3-Nitro-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C10H15ClN4O2 and a molecular weight of 258.70. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those with piperidine and nitro-pyridine pharmacophores.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Kinase Inhibitor Development: Serves as a precursor in the creation of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of chemical probes to study enzyme function and cellular signaling pathways.
• Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client R&D programs.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	(3-Nitro-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride
CAS No.	1185316-09-9
Molecular Formula	C10H15ClN4O2
Molecular Weight	258.70 g/mol
Synonyms	4-[(3-Nitropyridin-2-yl)amino]piperidine hydrochloride; 1-(3-Nitro-2-pyridinyl)-4-piperidinamine hydrochloride; 2-[(4-Aminopiperidin-1-yl)]-3-nitropyridine hydrochloride; 4-Amino-1-(3-nitropyridin-2-yl)piperidinium chloride; N-(3-Nitropyridin-2-yl)piperidin-4-amine hydrochloride; Piperidin-4-amine, N-(3-nitropyridin-2-yl)-, hydrochloride; 1185316-09-9 (CAS)
EINECS	Contact for details

Quality Control

Our (3-Nitro-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and identity criteria. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.