Description

(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride is a high-purity (98+%) organic salt with the molecular formula C11H14Cl2F3N3 and a molecular weight of 316.15. This compound is a key pharmaceutical intermediate and agrochemical building block, valued for its structural complexity and functional groups that enable targeted synthesis. It is primarily sought by R&D and process development teams in the pharmaceutical, crop protection, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, insecticides, and fungicides, leveraging the pyridine and trifluoromethyl motifs for enhanced bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Precursor: The amine and heterocyclic structure make it a candidate for developing specialized ligands in catalytic systems.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride
CAS No.	1185315-66-5
Molecular Formula	C11H14Cl2F3N3
Molecular Weight	316.15 g/mol
Synonyms	4-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino]piperidine hydrochloride; 2-Piperidin-4-ylamino-3-chloro-5-trifluoromethylpyridine hydrochloride; 3-Chloro-5-trifluoromethyl-2-(4-piperidinylamino)pyridine hydrochloride; 4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-1-piperidinecarboxylic acid ethyl ester (related ester); 1185315-66-5; 2-(4-Aminopiperidin-1-yl)-3-chloro-5-(trifluoromethyl)pyridine hydrochloride (isomeric form)
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperidin-4-Yl-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the 98+% purity specification and identity are met. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.